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Topics - Kat Burton

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ECN webinars 2019 / 6th September 2019- ECN multivariate statistics webinar 2
The ECN committee are pleased to announce the second webinar in our series on multivariate statistics that will be delivered by Dr Claus Mayer:

Sparse multivariate methods and integration of omics data sets

Friday 6th September, 16:00-17:00 CET

Multivariate methods like principle component analysis (PCA) or partial least squares (PLS) are essential in revealing structure in high-dimensional omics type data, where the number of variables is typically much larger than the number of samples (p>>n). As useful as these methods are to study the relationship between samples the high number of variables obscures the interpretation which genes, proteins or metabolites contribute to the patterns we see. Sparse methods enforce the loadings of most variables to be 0, while still explaining much of the variation in the data and thus enable an easier biological interpretation of the results. Dr Mayer will introduce sparse versions of some commonly used multivariate methods and illustrate their use in data examples.
In a second part he will present methods that simultaneously analyse two (or more) data sets like Canonical Correlation Analysis (CCA) or Co-Inertia Analysis (CIA). These tools allow to study the joint influence of two sets of variables (eg. a transcriptomic and a proteomic data set) on the variation within samples while showing the relationship between the data sets at the same time.


Dr Claus Mayer is a senior statistician working for Biomathematics and Statistics Scotland. His main area of research in recent years has been the analysis of high-dimensional genomics data with a particular emphasis on gene expression studies (microarrays, RNAseq) and related areas (proteomics, methylation studies. Dr Mayer has worked on methods of integrating/combining such omics data sets from different sources like combining high-dimensional  data from different stages of an experiment in a group-sequential setting, conducting meta-analysis of comparable gene expression studies or integrating different types of omics data collected from the same samples. Dr Mayer has also investigated ways of quickly calculating overall summary statistics of pairwise (cross-) correlations within one or more high-dimensional data sets and has studied ways of turning such (partial) correlation structures into sparse biologically interpretable networks.

Sign up for the webinar at:

https://attendee.gotowebinar.com/register/5674949347539367939
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NuGO conference 2019 / ECN annual social 2019- Tuesday 10th September
Join us in Bern during NuGOweek 2019 for the NuGO ECN annual social !

This year there will be an adventure room, speed-networking, refreshments and more!

Don't miss out, participation is limited, please sign up on the NuGOweek 2019 registration homepage.

Further information is given in the attached flyer.

Many thanks to Michel Combes for the flyer design:)
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ECN webinars 2019 / 28th June 2019: ECN webinar on Multivariate statistics- part 1
The first webinar in a three part series on the theme of multivariate statistics in nutrition will be delivered by Maren Büttner 

How to uncover biological patterns in omics data
Friday 28th June, 16:00 CET

This webinar is targeted at researchers who are using (or plan to use) omic data such as metabolomics, proteomics or transcriptomics to address their research questions. The first part of the webinar will cover how to use principal component analysis (PCA) as a tool for dimensionality reduction and detection of biases. In addition, guidance will be provided on how to select the number of meaningful components and how to interpret the loadings of principal components (if necessary). The second part of the webinar will explore how to complete basic clustering, including hierarchical clustering (e.g. as used in dendrograms), and how to extract groups from it. A practical example of the typical workflow for these analyses will be provided with an R script example for those who use R programming.

Extensive knowledge in R programming is not essential to participate in the webinar but the application of some of the methods is demonstrated in the R environment.

To sign up, please register directly at: https://attendee.gotowebinar.com/register/674439732259279361
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Job announcements / Postdoc fellowships in ETH, Zurich, Switzerland
Finding Sustainable Sources of Nutrition

Future Food is a Swiss research initiative that provides opportunities to educate and train new talent around the food value chain by leveraging the complementary strengths of the Swiss academic and industrial research communities.

The 'fellowship' is a postdoc programme for exceptionally qualified young researchers who propose projects targeting future food issues such as nutrition, production, packaging and digital health. The fellowship provides personal research funds for three years, enabling fellows to work on their projects in a research laboratory anywhere in Switzerland with a “champion” in academia (the host professor at ETH Zurich or EPFL) and in industry (the industry partner).

Fellowships
The aim is to award up to ten fellowships each year. The actual number depends on how many candidates successfully complete a selection process culminating with a face-to-face interview. In addition to scientific skills, the personality and motivation of the candidates will also be considered. However, the main criterion for selection is scientific excellence combined with industrial relevance. The call for new research or translational projects is conducted once every year.

For further information, visit:
https://www.futurefoodtalents.org/
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Job announcements / Post doc job vacancy- Food Research Center (FoRC) application deadline 24.4.19
The Food Research Center (FoRC) has opened a selection for a post-doctoral fellowship linked to a study aiming to evaluate the effects of d-limonene on metabolism. FoRC is a research center supported by São Paulo Research Foundation (FAPESP), located at the School of Pharmaceutical Sciences, University of São Paulo in São Paulo, Brazil.

D-limonene is a monoterpene abundant in citrus fruits known for its hypoglycaemic and hypolipidemic effects. The focus of the study is to evaluate mechanisms of action not yet explored, aiming to understand how this compound can modulate metabolism and prevent chronic diseases. For this purpose, a study in animal models will be carried out and different metabolomics platforms as well as metagenomic and gene expression analysis will be employed to assess d-limonene effects.

The ideal candidate must have:
• Obtained the PhD degree in the last 7 years;
• Have formal training in analytical chemistry (bachelor degree in chemistry, biochemistry,
pharmacy or related areas);
• Demonstrated experience in targeted and untargeted metabolomics. This includes the operation of qToF and triple quadrupole mass spectrometers and familiarity with data analysis softwares and mass spectrometry databases;
• Experience in R for data analysis;
• Experience with metabolomics analysis applied to nutrition/ metabolism of phytochemicals;
• Be the first author in at least one scientific publication in an indexed journal.


Applicants must send a CV, motivation letter and one recommendation letter to forc@usp.br until 25/04/2019. A final decision will be made until the 05/05/2019. The estimated date to start the new position is 01/07/2019.
FAPESP post-doctoral fellowships consist of monthly allowances of R$7373,10 and additional grant equivalent to 15% of the monthly allowances to cover costs related to the research project. The fellowship is granted for 2 years, with the possibility of extension for 2 extra years. Applicants living further than 350 Km from São Paulo are entitled to a relocation allowance and covering of travel costs.
6
Job announcements / Job opening- AFI R&D Gut Health
A job opening that might be of interest to PhDs or post docs working in nutrition and gut health.
 
Arla foods Ingredients (AFI) are looking for a skilled nutrition research scientist within Gut Health & Disease to drive our research activities together with external academia partners. Different backgrounds are possible, but with the requirement of a PhD (or similar experience).
 
For further information, please consult:
 
https://www.arla.com/company/job-and-career/vacancies/nutrition-research-scientist-in-gut-health-disease-aarhus/
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ECN webinars 2019 / 25th March 2019: 9th ECN webinar on Pathway analysis
Pathway analysis in the nutritional field using PathVisio and WikiPathways

DATE: Monday, 25th March at 16:00 h (CET)
HOST: Dr. Susan Coort (Department of Bioinformatics-BiGCaT, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, NL)


The ECN are pleased to announce our 9th webinar that will address how pathway analysis in PathVisio can be performed and how it is applied in the nutritional field. The webinar will start with an explanation of the online biological pathway repository WikiPathways (www.wikipathways.org). It will be shown how pathways can be created and curated. Thereafter, pathway analysis of various types of omics data will be discussed. The overrepresentation analysis (ORA), the statistical method used, will be explained and it will be shown how the researcher can find affected biological processes based on molecular changes. The open-source pathway analysis tool, PathVisio (www.pathvisio.org), will be explained in detail. Both the statistical and visualization module within PathVisio will be addressed. Finally, several nutritional example studies will be described and the pathway results will be discussed.

Susan Coort is working as an assistant professor at the department of Bioinformatics-BiGCaT, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University.

REGISTRATION: Attendance is FREE but registration is required
Send an email to ECN NuGO with:

– Email subject ‘Registration to Online Webinar’
– Your full name

Space is limited and priority is given to ECN members on a first-come-first-served basis. Details for accessing the webinar will be sent upon registration.
8
External training / Proteomics course with grants available
 
We are pleased to announce an Advanced Proteomics course, organised by the Graduate School VLAG and the Laboratory of Biochemistry, Wageningen University and Research, will take place from 27th to 30th August 2019.

Three course grants are being offered by NuGO. These grants are only available for PhD students from one of the NuGO member organisations. For more information visit: https://www.vlaggraduateschool.nl/en/courses.htm

Note that the deadline for a grant application is: 22 February 2019 (and not 5 March as mentioned on the course pages).

One should register and besides that a CV, motivation letter from the applicant and a support letter from the supervisor should be send to: nugo@wur.nl
9
Symposiums / PhD Defense: Genetic Variations in Connection
Sign up for a one day symposium at Maastrict on the topic of:

“Genetic Variations In Connection; Understanding the Effects of Single Nucleotide Polymorphisms in their Biological Context”

Elisa Cirillo – PhD candidate @ BiGCaT – Department of Bioinformatics / Maastricht University

Supervisor: Prof. Dr. C.T.A. Evelo
Co-supervisors: dr. S.L.M. Coort, Dr. L.D. Parnell



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Registration before 16th January at:
https://docs.google.com/forms/d/e/1FAIpQLScgjlc1qXUoBz5urbeUQ_POG3XFdKz5f1swvsDZBbfhHeMzdw/viewform
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Upcoming external webinars / Metabolon webinar on demand: Metabolomic profiling and gene function

Metabolon are hosting an 'on-demand' webinar entitled:

How Metabolomic Profiling Can Unlock Gene Function & Provide Biological Insight

In this webinar, you'll learn how the precise measurement of metabolites in an untargeted manner and this data can be used to unlock existing -omics data streams to understand the basis of wellness and disease.

Presented by:
Gregory Michelotti, PhD
Senior Study Director, Metabolon

Registration and further information available at:
https://learn.metabolon.com/how-metabolomic-profiling-can-unlock-gene-function-provide-biological-insight
11
ECN webinars 2019 / ECN 8th Webinar- personalised nutrition
The ECN committee are pleased to announce our 8th online webinar:

“Nutrition systems and health research for designing personalized solutions”

Colleen Draper M.S., R.D.,  from Nestlé Institute of Health Sciences SA (Switzerland), will share her insights about nutrition systems and health research for designing personalized solutions.

Date:
Tuesday 15 January at 16:00h (CET).

Registration:
Attendance is FREE but registration is required, limited space and attendance arranged based on ECN membership and order of registration.

To register please send us an email at ecn.nugo@gmail.com with:
* Email subject ‘Registration to Online Webinar’
* Your name and surname
12
PhD/training funding / NUGO EXCHANGE GRANTS – 2019, 1ST CALL
NuGO exchange grants for 2019 are now open!

The exchanges are foremost meant for temporary staff working with a NuGO member organisation (PhDs and postdocs < 5 years after obtaining their PhD). The host organisation should be a NuGO member organisation.

Total funding per exchange is € 3.500. This includes travel costs, board and lodging, and research costs if applicable, for travel to/from the member organisations in China, Australia and New Zealand we add € 500 for travel.

Minimum stay should be 10 working days, if combined with a conference visit then these conference days do not count
Max 1 application per member organisation, incoming and outgoing combined

From the applicant and the PI of the host institution we expect an active participation in NuGO activities (conferences, training courses, task-forces)

Exchanges are only possible between two NuGO member organisations.

Deadline for applications: March 1st, 2019

Applications should consist of a CV of 1- 2 pages and a description of the work to be done including the relevance for parties involved (1 page) as well as a draft budget.

Applications should be send to: nugo@wur.nl for the attention of Ingeborg van Leeuwen-Bol.


For further information, the Early Career Network (ECN) hosted a webinar on the topic of laboratory exchanges- during this webinar Prof Lorraine Brennen, NuGO CEO presented the importance of an exchange (see following link):

ECN webinar on laboratory exchanges
13
Job announcements / Job offer for PhD post in Nutritional Biochemistry
Rowett Institute, School of Medicine, Medical Sciences, and Nutrition at the University of Aberdeen is advertising a fully-funded, four-year PhD studentship in Nutritional Biochemistry:

“Investigating the effect of underutilised, emerging, polyphenol-rich berries on cardiometabolic health”

The studentship is available to UK/EU applicants only.

Closing date: 5th December 2018

Further information is available at https://www.findaphd.com/search/ProjectDetails.aspx?PJID=100764
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NuGO training / NuGO Post-Graduate course 2018
Temperature and Metabolism: Implications for nutritional studies

Who?
PhD students and postdoctoral researchers interested in whole body metabolism and translatability from mouse to human.

When?
1-3 September 2018, Newcastle upon Tyne, UK

Course leaders:
Prof. Jaap Keijer, Dr. Evert van Schothorst – Wageningen University & Research (The Netherlands), Dr. Fré Pepping – Wageningen University/NuGO secretariat (The Netherlands)

Post-graduate courses/workshops have been held on several occasions just prior to NuGOweek offering PhD students and postdoctoral researchers an opportunity to attend a training course and a scientific meeting with no additional costs.
This year the post-graduate course will be held in Newcastle University.

For more details visit the course page:
http://www.nugo.org/nugo-week/nugoweek-2018/post-graduate-course-temperature-and-metabolism-implications-for-nutritional-studies/